CLINICO-EPIDEMIOLOGICAL STUDY OF CONGENITAL ICHTHYOSIS IN A TERTIARY CARE CENTER OF EASTERN INDIA



Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.

Forward genetics screens with N-ethyl-N-nitrosourea (ENU) provide a powerful way to illuminate gene function and generate mouse pica limon packets models of human disease; however, the identification of causative mutations remains a limiting step.Current strategies depend on conventional mapping, so the propagation of affected mice requires non-let

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